
WHO and Africa CDC welcomed an initial allocation of 70,000 Ervebo vaccine doses to the Democratic Republic of the Congo on 20 August. The release from the global stockpile followed a government request for help responding to the Bundibugyo virus outbreak.
Of the allocation, 20,000 doses were intended for a Phase 3 trial and 50,000 for frontline and health workers under current expert recommendations. Ervebo is licensed against Ebola virus disease associated with the previously named Zaire ebolavirus; protection against Bundibugyo virus in humans had not been established. The clinical trial therefore serves an evidence-generating role. WHO stressed informed consent and clear communication about possible benefits, risks and limitations, alongside a response led with affected communities.